Netflix uses more than one CDN, and, according to posts by their one of their architects (Adrian Cockroft http://perfcap.blogspot.com/), they use EC2 for everything but some basic in-house HR/backoffice stuff.
He's got DOZENS of posts on how it works for them, how they full embraced ec2, etc. and how well it's working for them.
He's got DOZENS of posts on how it works for them, how they full embraced ec2, etc. and how well it's working for them.